I use this for diarrhea in puppies caused by coccidia that doesn't respond to Albon. I put it in their morning and evening meal. It has a very bitter taste so you might need to add some canned food if they are reluctant to eat it. My puppies never seemed to mind. If your puppies are not eating puppy food yet, you can mix the dosage with yogurt or Gerber Beef and Gravy baby food and give it with a syringe. When you mix tylan powder with water it won't mix right away. Store the mixture in the fridge and wait for the powder to be totally absorbed before using it. I start my puppies routinely at 3 weeks. I also take a stool sample in at this time to check for other parasites. AS ALWAYS check with your vet before administration of this antibiotic to your puppies.
Here are some on line sources for Tylan Soluble
Powder 100 gm. This is by no means a complete list.